Recent advancement in the stem cell field has led to the development of novel 3D cell culture models called organoids that mimic cell type diversity and architecture during organogenesis. Brain organoids, derived from human embryonic stem cells or induced pluripotent stem cells, capture key features of the developing human brain, including stem cell pool expansion, neurogenesis, gliogenesis, synaptogenesis and cytoarchitecture formation with cellular diversity and complexity. Organoids can also be derived from patient tumor samples, such as glioblastoma, for modelling brain tumors. In less than a decade, brain organoids have already been shown to be an extremely valuable tool to understand the human brain, and novel insights have been gained in deciphering evolution, human-specific features related to the brain development and neurological diseases resulted from pathogen infection, environmental insult, or genetic mutations.
In this course, we will take a multi-disciplinary approach to show what we could learn from brain organoid technology and what the future holds. The keynote speakers are all leaders in the field and will showcase the most up-to-date knowledge of brain organoids.
Topics & Techniques
More information soon
Bordeaux School of Neuroscience, France
The Bordeaux School of Neuroscience is part of Bordeaux Neurocampus, the Neuroscience Department of the University of Bordeaux. Christophe Mulle, its current director, founded it in 2015. Throughout the year, renowned scientists, promising young researchers and many students from any geographical horizon come to the School.
The school works on this principle: training in neuroscience research through experimental practice, within the framework of a real research laboratory.
Their dedicated laboratory (500m2), available for about 20 trainees, is equipped with a wet lab, an in vitro and in vivo electrophysiology room, IT facilities, a standard cellular imaging room, an animal facility equipped for behavior studies and surgery and catering/meeting spaces. They also have access to high-level core facilities within the University of Bordeaux. They offer their services to international training teams who wish to organize courses in all fields of neuroscience thanks to a dedicated staff for the full logistics (travels, accommodation, on-site catering, social events) and administration and 2 scientific managers in support of the experimentation.
Fee : 3.500 € (includes tuition fee, accommodation and meals)
Applications open in April 2022
The CAJAL programme offers 4 stipends per course (waived registration fee, not including travel expenses). Please apply through the course online application form. In order to identify candidates in real need of a stipend, any grant applicant is encouraged to first request funds from their lab, institution or government.
Kindly note that if you benefited from a Cajal stipend in the past, you are no longer eligible to receive this kind of funding. However other types of funding (such as partial travel grants from sponsors) might be made available after the participants selection pro- cess, depending on the course.