Extracellular Electrophysiology Acquisition is a Cajal NeuroKit. NeuroKits are hybrid courses that combine online lectures about fundamentals and advanced neuroscience topics, with hands-on and physical experiments.
Researchers from all over the world can participate thanks to the course material sent by post in a kit box containing all the tools needed to follow the online course.
Any data we collect has been shaped by the system we used to record it. Understanding the tools involved in data acquisition gives you the confidence to make informed experimental design choices, and the freedom to combine and try new approaches while building your dream setup.
In this course, we will develop your understanding of electrophysiology data acquisition. In terms of hardware, you will learn how acquisition systems can amplify tiny signals and filter out noise. You’ll test this understanding by building your own system to measure muscle and heart signals. In software, you will encounter synchronisation considerations, as we add incoming datastreams and build an increasingly complex experimental design.
Don’t be discouraged if you secretly panic at the mention of capacitance, this course starts from the very basics. Advanced students can make the final project as challenging as they like.
Designed by Open Ephys and Open Ephys Production Site, this course will have an open-source flavour and encourage you to try new ideas, share your insights, and connect with the open-source community.
What will you learn?
By the end of the course, you will:
be familiar with the electronic building blocks of acquisition systems
be able to model and build circuits to amplify and filter incoming signals
be able to use the Bonsai programming language to stream data and run closed-loop experiments with multiple datastreams
Open Ephys Production Site, PT
MIT and Open Ephys, USA
Open Ephys Production Site, PT
Aarón Cuevas López – Universitat Politècnica de València, ES
Joana Neto, FCT NOVA, PT
Jonathan P. Newman – MIT and Open Ephys, USA
Josh Siegle, Allen Institute, USA
Day 1 – Introduction
What are we trying to measure? Electrical signals in the brain and ways to record them.
How can we collect these signals without changing them? Considerations when building an acquisition system.
Using a simulator to visualise electrical circuits online and make predictions about real-world circuits.
Using the breadboard and components in your kit to test your understanding of electronics concepts.
Day 2 – Impedance
Using microcontrollers to acquire physiological data.
What is impedance? Understanding how we protect our signals while measuring them.
Understanding the function and limitations of operational amplifiers.
Day 3 – Data Acquisition
Understanding Instrumentation Amplifiers.
Simulating, building and testing low & high-pass filters.
Visualise your own EMG/ECG data using the Bonsai programming language.
Day 4 – Synchronizing Datastreams
Expanding on Bonsai – controlling cameras, receiving other datastreams.
Understanding closed-loop experiments, timestamp considerations, and synchronising datastreams.
Designing student projects and group feedback on plan.
Day 5 – Project and Open-Source Neuroscience
Open Ephys – open-source hardware & software development.
An overview of open-source community projects.
Student project presentation.
The courses will be held from 14:00 to 18:00 GMT.
Fee : 400€ (includes lectures and kit)