Course overview

The normal aging process is associated with reduced performance on cognitive tasks that
require one to quickly process or transform information to make a decision, including
measures of speed of processing, executive cognitive function, working and relational
memories. Structural and functional alterations in the brain correlate with these age-related
cognitive changes, such as loss of synapses, and dysfunction of neuronal networks. It is
crucial to develop new approaches that consider the whole neuroanatomical, endocrine,
immunological, vascular and cellular changes impacting on cognition.

This 3-week course will cover the fundamentals of cognitive aging -including inter-individual
differences, cognitive and brain reserve and risk factors- and highlight the newest functional
imaging methods to study human brain function. The Faculty will share the state-of-the-art
molecular, optical, computational, electrophysiological, behavioral and epidemiological
approaches available for studying the aging brain in diverse model systems.

Students will learn the potential and limitations of these methods, through practical
experience in a combination of lectures addressing aging in both humans and animal models
and hands-on-projects. They will acquire sufficient practical experience to model, design and
interpret experiments and brainstorm on novel technologies and hypotheses to explore the
aging of the brain using more integrative and creative approaches.

Course partners


Luísa V. Lopes

Course Director

iMM Lisboa, PT

Cheryl L. Grady


Baycrest and Univ. Toronto, Canada)

Nora Abrous


NeuroCentre, Bordeaux, FR

Keynote Speakers

This list will be updated soon


This list will be updated soon

Bordeaux School of Neuroscience, France

The Bordeaux School of Neuroscience is part of Bordeaux Neurocampus, the Neuroscience Department of the University of Bordeaux. Christophe Mulle, its current director, founded it in 2015. Throughout the year, renowned scientists, promising young researchers and many students from any geographical horizon come to the School.
The school works on this principle: training in neuroscience research through experimental practice, within the framework of a real research laboratory.

Their dedicated laboratory (500m2), available for about 20 trainees, is equipped with a wet lab, an in vitro and in vivo electrophysiology room, IT facilities, a standard cellular imaging room, an animal facility equipped for behavior studies and surgery and catering/meeting spaces. They also have access to high-level core facilities within the University of Bordeaux. They offer their services to international training teams who wish to organize courses in all fields of neuroscience thanks to a dedicated staff for the full logistics (travels, accommodation, on-site catering, social events) and administration and 2 scientific managers in support of the experimentation.


Fee : 3.500 € (includes tuition fee, accommodation and meals)

The CAJAL programme offers 4 stipends per course (waived registration fee, not including travel expenses). Please apply through the course online application form. In order to identify candidates in real need of a stipend, any grant applicant is encouraged to first request funds from their lab, institution or government.

Kindly note that if you benefited from a Cajal stipend in the past, you are no longer eligible to receive this kind of funding. However other types of funding (such as partial travel grants from sponsors) might be made available after the participants selection pro- cess, depending on the course.