Course overview

This inaugural Cajal Course on Neurobiology of Sleep offers a comprehensive overview of current knowledge, and existing gaps, in sleep regulation and its functions, and the dynamics of brain activity during sleep across species. World-leading experts in the field will guide participants through the latest advancements.

The course features hands-on training across a variety of cutting-edge approaches in the fields of brain imaging, recordings, manipulations, computational modelling, and data analysis. It also provides a comparative approach with different animal models and human research.

By applying these diverse techniques to sleep research, participants will significantly advance their knowledge in sleep science and master a wide array of advanced tools and methodologies.

Course directors

Carolina Gutierrez Herrera

University of Bern, Switzerland

Arthur Leblois

University of Bordeaux, France

julie seibt

Julie Seibt

University of Surrey, UK

Keynote Speakers

Antoine Adamantidis, University of Bern, Switzerland
Athina Tzovara, University of Bern, Switzerland
Bill Wisden, Imperial College London, UK
Charlotte Boccara, University of Copenhagen, Norway
Derk-Jan Dijk, University of Surrey, UK
Francesca Siclari, Netherland Institute for Neuroscience
Gabrielle Girardeau, Centre de Neuroscience de Sorbonne Université, France
Giorgio Gilestro, Imperial College London, UK
Lisa Roux, Bordeaux Neurocampus, France
Mark Blumberg, University of Iowa, USA
Markus Schmidt, University of Bern, Switzerland
Paul Antoine Libourel, Neurosciences Research Center of Lyon/Center for Functional and Evolutionary Ecology Montpellier, France
Peter Meerlo, University of Groningen, Netherland
Pierre Philip, Bordeaux Neurocampus, France
Robbert Havekes, University of Groningen, Netherlands
Sanne Moorman, University of Groningen, Netherlands
Yuval Nir, Tel Aviv University, Israel

Instructors

Alex Rosi, University of Bern, Switzerland
Cantin Ortiz
University of Oslo, Norway
Camille Mazo, University of Bordeaux, France
Carmen Guerrero Marquez
University of Bordeaux, France
Farahnaz  FaraghehUniversity of Surrey, UK
Flavio Schmidig, Tel Aviv University, Israel
Florence AellenUniversity of Bern, Switzerland
Haseeb JavedParis Brain Institute, France
Jenna Xie
Imperial College London, UK
Jessica Bruijel, Netherland Institute for Neuroscience
Kiran RavindranUniversity of Surrey, UK
Massimiliano Coscia, University of Groningen, Netherlands
Sara Wong, Imperial College London, UK
Solomiia KorchynskaUniversity of Oslo, Norway
Tim GervoisUniversity of Bordeaux, France
Yudong Yan, University of Bern, Switzerland

 

Course Content and Techniques

Sleep regulation and functions

• Regulatory mechanisms in humans and animals

• Overview of sleep function

• NREM and REM sleep

• Memory and synaptic plasticity

Neural circuit and activity

• Network and circuit dynamics during sleep

• Cell-type-specific activity

• Subcellular and dendritic compartment activity

Evolutionary & developmental perspectives

• Sleep ontogeny

• Sleep phylogeny

In vivo imaging
     • Neuron-astrocyte imaging
     • Two photon calcium imaging in dendrites
     • Fiber photometry

Electrophysiology
     • Human high-density EEG recording
     • Wearables for sleep monitoring
     • Neuropixels
     • Recordings in developing rodents
     • Wireless recording advances

Manipulations
     • Optogenetics
     • Chemogenetics
     • Auditory stimulation in humans
     • Sleep deprivation protocols

Molecular & behavioural
     • Omics approaches
     • Learning and memory tasks

Data science & modelling
     • Advanced analysis of big data
     • Computational modelling
     • Comparative approach across species

Bordeaux School of Neuroscience, France

The Bordeaux School of Neuroscience is part of Bordeaux Neurocampus, the Neuroscience Department of the University of Bordeaux. Created in 2015, it is currently directed by David Perrais. Throughout the year, renowned scientists, promising young researchers and many students from any geographical horizon come to the School.
The school works on this principle: training in neuroscience research through experimental practice, within the framework of a real research laboratory.

Facilities
Their dedicated laboratory (500m2), available for about 20 trainees, is equipped with a wet lab, an in vitro and in vivo electrophysiology room, IT facilities, a standard cellular imaging room, an animal facility equipped for behavior studies and surgery and catering/meeting spaces. They also have access to high-level core facilities within the University of Bordeaux. They offer their services to international training teams who wish to organize courses in all fields of neuroscience thanks to a dedicated staff for the full logistics (travels, accommodation, on-site catering, social events) and administration and 2 scientific managers in support of the experimentation.

Registration

Fee: 4.500 € (includes tuition fee, accommodation and meals)

Apply by July 3!